Brian Helfand, MD, PhD

Brian T. Helfand, MD, a urologist at Endeavor Health, specializes in urologic oncology and the treatment of prostate conditions. His clinical expertise includes minimally invasive surgery, advanced laparoscopy and procedures using the da Vinci robotic system. Dr. Helfand treats conditions such as benign prostatic hyperplasia, prostate cancer and urinary dysfunction using personalized and evidence-based approaches.

https://www.endeavorhealth.org/providers/brian-helfand

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2026 Men’s Health Conference BPH Resources

• Aquablation Official Website
  https://aquablation.com

• WATER Trial (Aquablation for BPH)
  https://clinicaltrials.gov/study/NCT02505919

• WATER II Trial (Aquablation for Large Prostates)
  https://clinicaltrials.gov/study/NCT03123250

• WATER FORWARD Trial (Aquablation vs. Radical Prostatectomy)
  https://clinicaltrials.gov/study/NCT05841147

• Aquablation 5-Year Outcomes (Gilling et al., J Urol 2022)
  https://pubmed.ncbi.nlm.nih.gov/35150215/

• TULSA-PRO Official Website
  https://tulsaprocedure.com

• TACT Trial (TULSA-PRO Pivotal Trial)
  https://clinicaltrials.gov/study/NCT02766543

• TULSA-PRO 5-Year Outcomes
  https://pubmed.ncbi.nlm.nih.gov/38388030/

• Rezūm Water Vapor Therapy
  https://www.rezum.com

• Rezūm 5-Year Outcomes (McVary et al.)
  https://pubmed.ncbi.nlm.nih.gov/33872051/

• Vanquish Water Vapor Ablation
  https://www.vanquishwaterablation.com

• VAPOR I Trial (Vanquish)
  https://clinicaltrials.gov/study/NCT05061134

• VAPOR II Trial (Vanquish)
  https://clinicaltrials.gov/study/NCT05683691

• ProtecT Trial (15-Year Outcomes)
  https://www.nejm.org/doi/full/10.1056/NEJMoa2214122

• NIH Summary of the ProtecT Trial
  https://www.cancer.gov/news-events/cancer-currents-blog/2023/prostate-cancer-protect-trial-15-year-results

• Prostate Cancer Prevention Trial (PCPT)
  https://www.cancer.gov/types/prostate/research/prostate-cancer-prevention-trial

• REDUCE Trial (Dutasteride)
  https://pubmed.ncbi.nlm.nih.gov/20357281/

• REDEEM Trial (Dutasteride During Active Surveillance)
  https://pubmed.ncbi.nlm.nih.gov/22277570/

• Shared Genetic Basis of BPH and Prostate Cancer (Helfand et al.)
  https://pubmed.ncbi.nlm.nih.gov/38703917/